课题名称 | 新疆蜱传人兽共患无浆体病新型检测技术的开发 Development of new detection technology of tick-borne disease anaplasmosis in Xinjiang | ||
执行时间 | 2013年 1 月-2015年12 月 | 课题编号 | 2013911061 |
项目来源 | 自治区科技厅科支疆办 | 资助经费 | 30 万 |
主 持 人 | 巴音查汗 | 结 题 否 | 在研 |
成 员 | 郭庆勇、宋振辉、王振宝、林涛、王真、张玉婷、吴敏、廖敏、孟元 | ||
摘 要 | 无浆体病（Anaplasmosis）是无浆体属的病原寄生于牛、羊、鹿等反刍动物红细胞内，由蜱媒传播而引起的疾病。牛死亡率可达10-80%，危害极大，还可传染人导致人兽共患病。由于新疆土地面积大、宿主动物泛多、生态植被复杂等原因，每年新增的媒介蜱虫及其传播无浆体等种类多样化和复杂化；加之，在我区该病与蜱传梨形虫病（俗称焦虫病）往往混合感染，流行严重，然而其新增媒介蜱虫种类及蜱传无浆体病的新型检测技术方面研究报道甚少。 本研究在前期工作基础上，与浙江大学合作，吸收、借鉴先进技术，从媒介蜱虫和感染无浆体的宿主动物两方面入手，从地方阳性病例及媒介蜱体分离菌株、鉴定及接种动物、保存菌株；研究我区无浆体病媒介蜱虫种类（包括新增媒介），掌握蜱传无浆体病在我区的流行特点；借助浙江大学分子生物学研究平台，开发研究我区牛羊无浆体及其传播蜱的分子免疫学检测、诊断新技术，早期及时发现蜱虫害及无浆体病，正确评估我区无浆体病的危害程度，为拟定适合我区‘干旱植被型’蜱虫及其传播无浆体的综合防控提供技术支撑。
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Abstract | Anaplasmosis is caused by paranaplasma which parasitic in red blood cell of cattle, sheep ，deer and other ruminant animals and it was Tick-Borne Disease.The Anaplasmosis will do great harm to the aquaculture and which can result in mortality up to 10 to 80% and can cause zoonosis. Because of a large of area of Xinjiang，host animal is various，complex vegetations and ecological environment, the new vector ticks and Anaplasma species spread diversification and complication in every year ，In addition，this disease is mixed with piroplasmosis in our region，and it is seriously prevalent，However，There has been few reports on the new detection technique with the new vector ticks species and Anaplasma. Under the foundation of this study，cooperation with zhejiang university，absorb advanced technology，Starting from two aspects of the vector ticks and Anaplasma infection of host animals. Isolates，i dentification and vaccinated animals，save strains ；from local Positive cases and vector ticks(include new vector ticks)，Grasp the tick-borne anaplasmosis popular features in my area；Development research the Cattle and sheep anaplasmosis and vector ticks molecular immunology diagnostic diagnostic technique with Zhejiang University in molecular biology research platform ，As is early detection Tick Pest and Anaplasmosis，correct assessment the degree of Anaplasmosis harm in our region. In order to make measures of the comprehensive prevention and control methods of ticks and Tick-borne Anaplasma in our region ‘Arid vegetation types’.
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