课题名称 | 新疆自然放牧区域蜱虫种群分布及其蜱传病地方流行关系的研究 Study on the population distribution of ticks and the relationship to local epidemic of major tick-borne disease in natural grazing areas in Xinjiang | ||
执行时间 | 2012年 1 月-2014年12 月 | 课题编号 | NSFC- U1170301 |
项目来源 | 国家自然科学基金委 | 资助经费 | 50 万 |
主 持 人 | 巴音查汗 | 结 题 否 | 在研 |
成 员 | 张厚双、 龚海燕、刘启生、王真、曹雯丽 | ||
摘 要 | 新疆幅员广阔，地理区系复杂，在新疆境内分布的蜱虫种类占全国之首，每年有80%的自然放牧动物被蜱虫叮咬及发生蜱媒病，危害极大。本研究在前期工作基础上，与中国农业科学院上海兽医研究所合作，从新疆自然放牧区域环境中硬蜱和畜体硬蜱两个来源入手，在不同季节采集，确定种类，发育阶段，动物体表感染强度和感染率等；探究地方优势分布媒介硬蜱种类及其携带病原体情况及流行病学特点，并对其主要病原微生物（如梨形虫、无浆体、细菌、病毒）进行分离、鉴定、体外培养及基因分析，确定不同区域、不同季节、不同来源、不同蜱种的病原菌（虫、病毒等）种类，感染率等。同时，建立特异、敏感的蜱传病检测技术。根据新疆自然放牧地带优势分布硬蜱种群及其传播地方高发病流行特点进行综合分析，提出防治重点，建立我国新疆媒介硬蜱体内携带病原体的种类、强度、季节动态和风险评估的信息数据库，为蜱传病的预警和防治提供基础资料，以保障草地畜牧业的健康发展。
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Abstract | Xinjiang is a broad region and complex in geographical area. The distribution of the tick species in Xinjiang was accounted for the first in China. There are 80% natural grazing animals which were bited by ticks followed suffered tick-borne disease. The present study will be carried out based on the previous studies and will be coorperated with Shanghai Veternary Research Institute,Chinese Academy of Agricultural Sciences. In different seasons, hard ticks from two sources,Xinjiang nature grazing environment and domestic animal body, will be collected and determine the species, the developmental stage, the intensity of infection and the infection rate of animal skin. The local predominant distribution vector tick species and their carrying pathogen and epidemiology characteristics will be explored followed isolation,identification, cultured in vitro and gene analysis their main pathogenic microorganisms, such as Piroplasmeas,Anaplasmas, bacteria and virus.The species and infection rates of pathogenic bacteria, such as protozoa and virus, from different regions,seasons and sources will be confirmed. Moreover, the specific and sensitive detection methods of tick-borne disease will be established. According to the above studies, the database including pathogenic species, their population, seasonal chances and risk assessment of vector ticks in Xinjiang will be established. The main prevention methods will be given. This study will provide the basic information for early warning and prevention of tick-born diseases and ensure the development of animal husbandry which is related with grassland.
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